BIOSYS logo Biophysics of complex systems

Welcome to Biophysics of complex systems

A research lab focused on biophysics and molecular dynamics applied to biological complex systems.

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About Our Team

Our group, hosted by the Institut des Sciences Analytiques, focuses on the structural and dynamical characterization of intrinsically disordered and multi-domain proteins related to some important biological questions, namely, the bacterial silver resistance and schistosomiasis chronic parasitic disease. We are also developing fundamental approach aiming at combining biophysical methods with molecular dynamics simulations.  For this purpose, we use NMR (Nuclear Magnetic Resonance), X-ray crystallography, Small angle X-ray and neutron scattering (SAXS, SANS), circular dichroism, Raman spectroscopy and High Performance computing.

image of the BIOSYS's team members

Latest Publications

Mechanism of Ag+-induced Folding of a Bacterial Peptide from Replica-Exchange Molecular Simulations

ChemRxiv. 2025

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Molecular dynamics as an efficient process to predict 15N chemical shift anisotropy at very high NMR magnetic field.

Phys. Chem. Chem. Phys, 2025, 27, 2320-2332

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Impact of conditioning runs on hydrophilic interaction chromatography repeatability and its application as a second dimension in online comprehensive two-dimensional liquid chromatography

J. Sep. Sci., 2024, 47 (9-10), 2300935

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News

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Archifun project, MSCA Cofund from 2024 to 2029

The ArchiFun project has been granted through MSCA Cofund from 2024 to 2029. It consists of a doctorate program joining several universities: University of Lyon (France), University of Granada (Spain), University of Padova (Italy), Technical University of Munich (Germany), National Institute of Chemistry Ljubljana (Slovenia).

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Cover of PCCP 25th Anniversary

Our article «Molecular dynamics as an efficient process to predict 15N chemical shift anisotropy at very high NMR magnetic field» has been selected to illustrate the front cover of PCCP 25th anniversary.