Biophysics of complex systems

Institut des Sciences Analytiques

UMR CNRS 5280 - Université Lyon1

5 rue de la Doua

Villeurbanne - FRANCE

Our group focuses on the structural and dynamical characterization of intrinsically disordered and multi-domain proteins related to some important biological questions, namely, the bacterial silver resistance and schistosomiasis chronic parasitic disease. We are also developing fundamental approach aiming at combining biophysical methods with molecular dynamics simulations.  For this purpose, we use NMR (Nuclear Magnetic Resonance), Small angle X-ray and neutron scattering (SAXS,SANS), circular dichroism, Raman spectroscopy and High Performance computing.


  • The ARBRE association (Association of Resources for Biophysical Research in Europe), managed by Prof. Adriana Erica Miele has been officially released 
Chemical communications front cover
  • Our original study on the interplay between the disordered C-terminal of SilB and SilE in the presence of silver binding has been published in Chemical Communcations and has been selected to appear in front cover of the journal 
  • Welcome to Prof. Adriana Erica Miele who has officially joined our group